Given the growing antibiotic resistance crisis, novel ways to target bacterial infections are becoming increasingly important. One potential strategy is to manipulate bacterial genes at the ...

The cartoon illustrates how single-cell transcriptomics works: all mRNA molecules are recorded and characterized from countless bacterial cells, which are shown here in survival size on a conveyor ...

Bioinformaticians from Heinrich Heine University Düsseldorf (HHU) and the university in Linköping (Sweden) have established that the genes in bacterial genomes are arranged in a meaningful order. In ...

Bioinformaticians have established that the genes in bacterial genomes are arranged in a meaningful order. They describe that the genes are arranged by function: If they become increasingly important ...

Modern medicine depends on antibiotics to treat infections by disabling targets inside bacterial cells. Once inside these cells, antibiotics bind to certain sites on specific enzyme targets to stop ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

Drug-resistant bacteria are becoming harder to treat, pushing scientists to look for new antibiotic targets. Researchers have now discovered that several unrelated viruses disable a key bacterial ...

With such striking effects, many scientists see modulating the microbiomes as a promising avenue for improving human health and wellbeing. In recent years, researchers have shown that tweaking the ...

siMecA-AGO2 complex inhibits the translation of the mecA gene which encodes the penicillin-binding protein 2a (PBP2a), a protein at the heart of the drug-resistance phenotype in MRSA. By reducing ...

Scientists found an unexpected viral hitchhiker lurking inside a common gut bacterium – and it was twice as prevalent in people with colorectal cancer.